Butt, M.S. During the glycation process, the oxidative degradation of Amadori intermediates generates superoxide anion such as 1,2- and 2,3-enolization of the Schiff’s base causing oxidative damage to protein detected by increasing formation of protein carbonyl and depleting protein thiol group [, Glycated hemoglobin (Amadori products) is also produced from non-enzymatic glycation between glucose and N-terminal amino acids of beta chains of hemoglobin. ; Katiyar, C.; Kanaujia, A.; Duggar, R.; Singh, Y.; Srinivas, K.; et al. Narasimhan, A.; Chinnaiyan, M.; Karundevi, B. Ferulic acid exerts its antidiabetic effect by modulating insulin-signalling molecules in the liver of high-fat diet and fructose-induced type-2 diabetic adult male rat. Bhattacharya, S.; Oksbjerg, N.; Young, J.F. Inhibition of the protein in tyrosine phosphatase PTP1B: Potential therapy for obesity, insulin resistance and type-2 diabetes mellitus. ; El-Said, A.M.; Khalifa, S.A.; Göransson, U.; Bohlin, L.; Borg-Karlson, A.K. Protective and anti-angiopathy effects of caffeic acid phenethyl ester against induced type 1 diabetes in vivo. The antioxidant activity of four derivatives of benzoic acid was systematically compared with the activity of the four homologous derivatives of cinnamic acid. with the reproduced material. ; Kim, J.S. Compound 6, one of two hit compounds, suppressed the viral replications of genotypes 1b, 2a, 3a, and 4a with EC ; Lai, T.Y. Meeprom, A.; Sompong, W.; Suantawee, T.; Thilavech, T.; Chan, C.B. ; Scalbert, A.; Knaze, V.; Romieu, I.; Slimani, N.; Fagherazzi, G.; Perquier, F.; Touillaud, M.; Molina-Montes, E.; et al. those of the individual authors and contributors and not of the publisher and the editor(s). ; Regenhard, P.; Müller, U.; Sauerwein, H.; Mielenz, M. trans-cinnamic acid increases adiponectin and the phosphorylation of AMP-activated protein kinase through G-protein-coupled receptor signaling in 3T3-L1 adipocytes. Tahrani, A.A.; Barnett, A.H.; Bailey, C.J. Konishi, Y.; Hitomi, Y.; Yoshioka, E. Intestinal absorption of. Inzucchi, S.E. Adolpho, L.O. Jayamani, J.; Shanmugam, G.; Singam, E.R.A. This group of compounds includes both naturally occurring as well as synthetic substances. Oral hypoglycemic agents: Insulin secretagogues, alpha-glucosidase inhibitors and insulin sensitizers. Aceituno-Medina, M.; Mendoza, S.; Rodríguez, B.A. The common cinnamic acid derivatives include p-coumaric acid, caffeic acid, and ferulic acid. Cinnamic acid is an organic acid occurring naturally in plants that has low toxicity and a broad spectrum of biological activities. Hydroxycinnamic acid derivatives are important class of polyphenolic compounds originated from the Mavolanate-Shikimate biosynthesis pathways in plants. Raptis, S.A.; Dimitriadis, G.D. Liu, I.M. ; El-Refaei, M.F. The worldwide epidemiology of type 2 diabetes mellitus—Present and future perspectives. ; Jeppesen, P.B. Constituents of the flowers of. The structure was confirmed by MS and 1H NMR. With recent insight into the development of dietary supplements and functional foods, search of effective phytochemical compounds and their mechanisms involved in prevention and management of diabetes and its complications are now being assessed. In vitro evaluation of caffeoyl and cinnamoyl derivatives as potential prolyl oligopeptidase inhibitors. ; Sultan, M.T. RESULTS Initial Identiﬁcation of GLIC Ligands Using a Library of Gloeobacter violaceus Metabolites. of the whole article in a thesis or dissertation. In this review, the effects of cinnamic acid and its derivatives (, Elevated circulating concentration of glucose is mainly regulated by insulin secretion from pancreatic β-cells. Authors contributing to RSC publications (journal articles, books or book chapters)
Standards of medical care in diabetes-2011. contained in this article in third party publications
The concept of ‘substrate engineering’ as opposed to ‘enzyme engineering’, offers a complimentary and faster approach to developing a bioprocess, making difficult transformations possible. ; López-Rubio, A. CICECO – Aveiro Institute of Materials and Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal. ; Bracht, A.; Constantin, J. Metabolic effects of. Inhibition of insulin amyloid fibril formation by ferulic acid, a natural compound found in many vegetables and fruits. Cinnamic acid is a central intermediate in the biosynthesis of a myriad of natural products including lignols (precursors to lignin and lignocellulose), flavonoids, isoflavonoids, coumarins, aurones, stilbenes, catechin, and phenylpropanoids.